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Wyeth Discovers Anti-Aging Pill by Accident -- It's Rapamune, an Organ Transplant Drug

By Jim Edwards | Jul 9, 2009

Wyeth told the WSJ that it did not know about a study published Wednesday in Nature that claims the age of mice was increased 9 - 14 percent if they took Rapamune, a drug Wyeth markets to suppress the immune system so that organ transplants won’t be rejected. A second study in Science was on monkeys.

When told it owned a potential fountain of youth by the WSJ:

A Wyeth spokesman called it an “interesting preclinical study” and said Wyeth just became aware of the finding Wednesday.

The idea that aging is a disease that can be treated is gaining ground among fringe believers. Some look at lifelong calorie restriction as a treatment. Others simply believe that technology can fix everything. An example:

“It’s time to break out of our denial about aging,” said Aubrey de Grey, a British gerontologist who has drawn controversy for his suggestions on how to forestall death. “Aging is, unequivocally, the major cause of death in the industrialized world and a perfectly legitimate target of medical intervention.”

Yes, aging is the “cause” of death, although to be strictly accurate I’d say that “death” was the real cause of death — humans can withstand aging for decades; but death has a 100 percent fatality rate.

Already, there will be some execs within Wyeth pondering a new indication application to the FDA. Some will be speculating about off-label promotions — after all, Pfizer made hundreds of millions of dollars selling its human growth hormone brand, Genotropin, to anti-aging quacks (before it was caught and punished by the feds).

One major advantage of selling an anti-aging pill: If the patient dies they will be less likely to sue.

Jim Edwards, a former managing editor of Adweek, has covered drug marketing at Brandweek for four years, and is a former Knight-Bagehot fellow at Columbia University's business and journalism schools. Follow him on Twitter or send him an email.

BNET User Analysis

Web Buzz:
  • Possible warning for use of Wyeth's Rapamune in transplants

    Scrip News - 145 days 14 hours 8 minutes ago

    The US FDA is to determine whether to make labelling changes to Wyeth's immunosuppressant Rapamune (sirolimus) following the results of a study which found that liver transplant patients who received the drug after conversion from a calcineurin

  • HTDS Reports Positive Experimental Results For Multiple Sclerosis Treatment

    Pharmaceutical Business Review - 81 days 14 hours 45 minutes ago

    Study showed the suppression of the immune cells, forcing remission and reversing the disease in mice

  • Treatment holds promise for transplant medicine

    ABC - 215 days 22 hours 14 minutes ago

    By national medical reporter Posted Australian scientists have uncovered a way of manipulating the immune system to stop transplanted organs being rejected. Patients who have an organ transplant need to take a cocktail of drugs to prevent the body rejecting an organ transplant and the medications can increase the risk of infection and cancer....

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    BOSTON—New research from the Jean Mayer USDA Human Nutrition Research Center on Aging at Tufts University (USDA HNRCA) suggests dietary curcumin may have a potential benefit in preventing obesity. Researcher found curcumin, a polyphenol found in turmeric, reduces weight gain and suppresses the growth of fat tissue in mice and cell...

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