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Icahn Moves on Amylin; Will Lilly Step Up?

By Jim Edwards | Jan 30, 2009

BNET’s 10-Q Detective, David Phillips, reports that Carl Icahn has filed papers to nominate a slate of directors for the board of Amylin, maker of diabetes drug Byetta.

The last time Icahn interfered with a smaller company, ImClone, it ended up being bought by Eli Lilly. Here’s Phillips’ description of Icahn’s motivation:

What’s Icahn’s interest in Amylin? Ill-timed purchases of stock in 2008 — in the mistaken belief that the shares were undervalued, according to a May 2008 regulatory filing. The billionaire investor’s position of approximately 11.4 million shares, acquired at an estimated purchase of $26.23 a share, has lost almost 58 percent in value, as prescription sales of Amylin’s lead product Byetta, the diabetes medication sold in partnership with Eli Lilly,  slowed to a crawl in the second-half 2008 after the FDA announced several severe cases of acute pancreatitis among patients taking the drug.

The obvious premium-payer for Icahn’s shares is, again, Eli Lilly. Lilly and Amylin already have a joint deal to market Byetta, Amylin’s second-line diabetes drug. Lilly’s sales force would not need to be educated on the drug.

Plus, the company isn’t worth a great deal. It has a market cap of about $1.5 billion, because Amylin only loses money.

Icahn may be hoping that Lilly or a rival could be tempted to move quickly, before the FDA adds any more drugs to an already crowded market. Forbes:

Both Byetta and LAR would likely face competition from Novo Nordisk’s developing liraglutide, which would be taken once-daily. Competition within the field is growing, with Merck & Co.’s Januvia already on the market, and Bristol-Myers Squibb Co. and AstraZeneca developing a treatment called saxagliptin.*

Icahn’s problem is that, with ImClone in hand and a potential approval of blockbuster prasugrel coming, Lilly needs Amylin much less than it used to.

That makes Amylin and Byetta relatively less attractive, especially given the hurdles Byetta has yet to overcome in the marketplace. (One example: Byetta isn’t on the New York Medicaid preferred drug list, which other reimbursers often take their cues from.)

*Disclosure: The author has a family member employed by an outside agency that works on this drug.

Tags: Jim Edwards

Jim Edwards, a former managing editor of Adweek, has covered drug marketing at Brandweek for four years, and is a former Knight-Bagehot fellow at Columbia University's business and journalism schools. Follow him on Twitter or send him an email.

BNET User Analysis

Web Buzz:
  • Amylin Battle Heats Up as Eastbourne Capital Touts Rival Directors' Slate to Icahn's

    BNET Pharma - 294 days 2 hours 54 minutes ago

    Eastbourne Capital has proposed a five-member team of its own for Amylin's board. Carl Icahn proposed his own slate last week. Both sets of investors are unhappy with the company that has a joint venture with Eli Lilly on diabetes drug Byetta. Eastbourne said of its move: Eastbourne is aware of Icahn Capital LP's nomination of a slate of five...

  • Amylin v. Icahn Slideshow Battle: Tear Up Lilly-Byetta Agreement!

    BNET Pharma - 200 days 11 hours 53 minutes ago

    Carl Icahn's shareholder presentation in the fight for control of Amylin's board of directors says that the company's joint venture with Eli Lilly on diabetes drug Byetta should be torn up and renegotiated

  • Icahn makes play for Amylin control

    Fierce Pharma - 297 days 8 hours 57 minutes ago

    Carl Icahn is at it again, and this time his target is Amylin Pharmaceuticals. The San Diego pharma--which is Eli Lilly's partner on the diabetes med Byetta--said Icahn Capital plans to nominate a slate of directors to the company's board. Already, Amylin directors are checking out two of Icahn's nominees. The fact that Icahn's making a play for...

  • Amylin Resists Icahn's Proposal to Sell Itself

    New York Times - 217 days 3 hours 27 minutes ago

    Amylin Pharmaceuticals is resisting the billionaire financier Carl C. Icahn's proposal that it sell itself to Eli Lilly, its diabetes drug-making partner. In a filing on Monday with the Securities and Exchange Commission, Amylin disclosed the proposal by Mr. Icahn and argued in a letter to him that such a deal would "dramatically undervalue" the

  • The ABCs of Lilly: Amylin, Byetta & Carl

    Seeking Alpha - 216 days 6 hours 32 minutes ago

    Mike Huckman submits: Shortly after Eli Lilly LLY reported way better than expected earnings yesterday morning, Amylin Pharmaceuticals AMLN fired a new salvo in its escalating proxy battle with billionaire activist investor Carl Icahn. LLY and AMLN are partners on the twice-a-day injectable diabetes drug Byetta, and

 

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